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Bone Therapeutics

Bone Therapeutics in brief

Bone Therapeutics is a biotechnology company with a unique approach to the development of cell therapy products for bone fracture repair and fracture prevention.

Bone Therapeutics is creating a new and unique treatment approach using differentiated bone-forming cells administered via a minimally invasive percutaneous procedure, that is expected to offer significant benefits over the current standard-of-care that often involves heavy surgery and long recovery periods.

Today, Bone Therapeutics has 2 first-in-class products, which target 6 indications and offer the potential for additional product extensions:

  • PREOB®, an autologous osteoblastic cell therapy product currently in 2 pivotal Phase IIB/III clinical trials in Europe for the treatment of osteonecrosis and non-union fractures, as well as in a Phase IIA for severe osteoporosis (treatment-resistant osteoporosis); and
  • ALLOB®, an allogeneic (“off-the-shelf”) osteoblastic cell therapy product currently in 3 Phase I/IIA proof-of-concept trials for the treatment of delayed-union fractures, spinal fusion procedures and revision spinal fusion.

In addition, Bone Therapeutics is conducting preclinical research on next generation products such as combined cell-matrix products for large bone defects and maxillofacial applications or enhanced viscosupplementation for osteoarthritis.

Bone Therapeutics’ cell therapy products are manufactured to the highest GMP standards and are protected by a rich Intellectual Property estate.

Bone Therapeutics portrayed in 'Z Life Sciences' series on Kanaal Z :  View the episode